Table 1.
Total (n = 156) | Fallers (n = 60, 38.5%) |
Non-fallers (n = 96, 61.5%) |
p-value | |
---|---|---|---|---|
Age (years), mean ± SD | 36.57 ± 11.35 | 41.33 ± 10.63 | 33.59 ± 10.15 | < 0.001 |
Gender, n (%) | 0.714 | |||
Female | 114 (73.1%) | 45 (75%) | 69 (71.9%) | |
Male | 42 (26.9) | 15 (25%) | 27 (28.1%) | |
EDSS (0–10), median (25th–75th percentile) | 1.5 (0–2.0) | 2.0 (1.5–5.5) | 1.0 (0–1.5) | < 0.001 |
MS course, n (%) | < 0.001 | |||
Relapsing–Remitting | 143 (91.7%) | 47 (78.3%) | 96 (100%) | |
Progressive | 13 (8.3%) | 13 (21.7%) | 0 (0) | |
Disease duration (years), median (25th–75th percentile) | 6 (2–11.38) | 8 (2.13–16.75) | 5 (2–10) | 0.016 |
Number of falls, median (25th–75th percentile) | 0 (0–1) | 1 (2–4) | N/A | N/A |
ABC (0–100), mean ± SD | 75.60 ± 23.53 | 57.87 ± 22.49 | 86.68 ± 16.33 | < 0.001 |
ABC-6 (0–100), mean ± SD | 67.63 ± 28.91 | 46.67 ± 26.63 | 80.74 ± 21.71 | < 0.001 |
SLST (sec), mean ± SD | 31.11 ± 24.85 | 19.42 ± 23.05 | 38.30 ± 23.23 | < 0.001 |
T25FW (sec), mean ± SD | 8.43 ± 20.37 | 13.69 ± 31.72 | 5.15 ± 4.88 | < 0.001 |
TUG (sec), mean ± SD | 9.19 ± 8.41 | 12.46 ± 10.09 | 7.26 ± 6.54 | < 0.001 |
TUG-Cog (sec), mean ± SD | 11.47 ± 11.65 | 15.55 ± 14.88 | 9.06 ± 8.42 | < 0.001 |
6MWT (m), mean ± SD | 429.58 ± 136.76 | 350.25 ± 168.07 | 478.33 ± 82.25 | < 0.001 |
SDMT (score), mean ± SD | 47.29 ± 12.41 | 43.93 ± 14.07 | 49.44 ± 10.77 | 0.01 |
*p < 0.05; p-value of independent t-test for continuous normal distributed data (mean ± SD), Mann–Whitney U test for non-normal distributed data [median (25th–75th percentile)], or chi-square for categorical variables
SD standard deviation; EDSS Expanded Disability Status Scale; ABC 16-item Activities-specific Balance Confidence; ABC-6 6-item Activities-specific Balance Confidence; SLST Single-Leg Stance Test; T25FW Timed 25-foot Walk; TUG Timed Up and Go; TUG-Cog Timed Up and Go test with cognitive task; 6MWT Six-Minute Walk Test; SDMT Symbol Digit Modalities Test