Table 3.

Esophageal dose comparison between the patient with grade 5 esophageal toxicity and other patients

	The TRD patient (N = 1) vs. other patients (N = 15)
	Dmax	D0.035 cc	D1cc
SBRT dose, maximum value [IQR]
EQD2
α/β = 2, Gy2	89 vs. 82 [32, 66]	80 vs. 74 [25, 58]	57 vs. 57 [15, 48]
α/β = 3, Gy3	76 vs. 70 [28, 57]	68 vs. 64 [22, 50]	50 vs. 49 [14, 42]
α/β = 10, Gy10	46 vs. 43 [20, 36]	42 vs. 40 [16, 32]	32 vs. 32 [11, 28]
BED
α/β = 2, Gy2	178 vs. 164 [63, 131]	160 vs. 148 [49, 116]	114 vs. 114 [29, 95]
α/β = 3, Gy3	127 vs. 117 [47, 95]	114 vs. 106 [37, 84]	83 vs. 82 [23, 69]
α/β = 10, Gy10	55 vs. 52 [24, 43]	51 vs. 48 [20, 39]	38 vs. 38 [13, 33]
Cumulative dose, maximum value [IQR]
EQD2
α/β = 2, Gy2	148 vs. 131 [76, 103]	136 vs. 120 [72, 101]	112 vs. 106 [66, 94]
α/β = 3, Gy3	136 vs. 122 [73, 96]	125 vs. 112 [70, 95]	105 vs. 100 [63, 90]
α/β = 10, Gy10	106 vs. 102 [74, 88]	100 vs. 97 [71, 87]	89 vs. 88 [65, 84]
BED
α/β = 2, Gy2	296 vs. 262 [152, 206]	272 vs. 240 [144, 202]	224 vs. 212 [132, 188]
α/β = 3, Gy3	227 vs. 203 [121, 160]	209 vs. 187 [117, 158]	175 vs. 167 [104, 150]
α/β = 10, Gy10	127 vs. 122 [89, 106]	120 vs. 117 [85, 104]	107 vs. 106 [78, 101]

EQD2 equivalent dose at 2 Gy, BED biological effective dose, IQR interquartile range, SBRT stereotactic body radiation therapy, Cumulative dose total dose accumulated SBRT dose and the initial external beam radiation therapy doses, D_max the maximum dose at one point of the target volume, D_0.035 cc the maximum dose that covered 0.035 cc of the target volume, D_1cc the maximum dose that covered 1 cc of the target volume