Table 1.
TOPMed dataset (training and testing sets combined) characteristics aggregated over the studies, stratified by self-reported race/ethnic background.
| Characteristic | White | Black | Hispanic/Latino | Asian | Other/unknown |
|---|---|---|---|---|---|
| N | 30,668 | 14,587 | 11,904 | 4655 | 481 |
| Gender (N (%)) | |||||
| Female | 20,218 (66%) | 9165 (63%) | 7108 (60%) | 2376 (51%) | 198 (41%) |
| Male | 10,450 (34%) | 5422 (37%) | 4796 (40%) | 2279 (49%) | 283 (59%) |
| Age, years (median, IQR)) | 60 (50, 69) | 55 (47, 64) | 52 (43, 61) | 48 (40, 57) | 59 (50, 67) |
| SBP, mmHg (median, IQR)) | 126 (113, 142) | 133 (119, 150) | 126 (113, 144) | 122 (110, 138) | 134 (116, 152) |
| DBP, mmHg (median, IQR)) | 75 (68,83) | 80 (72, 89) | 76 (68, 84) | 75 (68, 85) | 76 (66, 86) |
| BMI, kg/m2 (median, IQR)) | 26.4 (23.5, 30.0) | 29.0 (25.1, 34.0) | 29.0 (26.0, 33.0) | 23.9 (21.8, 26.2) | 27.3 (24.3, 31.5) |
| Hypertensive (N (%)) | 17,274 (56%) | 10,103 (69%) | 6733 (57%) | 2381 (51%) | 323 (67%) |
Hypertension was defined as SBP 130, DBP , or use of antihypertensive medications.
IQR interquartile range.