Table 3.
FICI values for UA and antibiotics when used to treat clinical S. aureus isolates.
| Clinical isolated S. aureus | S3 | S4 | S5 | S6 | S7 | T1 |
|---|---|---|---|---|---|---|
| UA | 1/4 | 1/4 | 1/4 | 1/2 | 1/4 | 1/4 |
| Ampicillin (MIC) | 1/2 | 1 | 1/8 | 1/4 | 1 | —— |
| Ceftiofur hydrochloride | —— | —— | —— | —— | —— | 1/8 |
| Fractional Inhibitory Concentration Indices (FICI) | 0.75 | 1.24 | 0.375 | 0.75 | 1.25 | 0.375 |
| The synergistic activities | Additive | No effect | Synergistic | Additive | No effect | Synergistic |
A FICI < 0.5, 0.5–0.75, 0.75–1, 1–4, and >4, respectively, indicated synergy, partial synergy, an additive effect, no effect, and antagonism, as per the European Committee for Antimicrobial Susceptibility Testing (EUCAST) criteria.