Table II.
Demographics and clinicopathological characteristics of patients with esophageal squamous cell carcinoma.
| Variable | High exosomal miR-185-5p group (n=28) | Low exosomal miR-185-5p group (n=61) | P-value |
|---|---|---|---|
| Mean age ± SD, years | 66.6±8.03 | 66.8±8.32 | 0.923a |
| Sex, n | |||
| Male/Female | 24/4 | 51/10 | >0.999b |
| Histological grade, n | |||
| G1/G2/G3/X | 4/15/7/2 | 11/29/13/8 | 0.853b |
| Location of the tumor | |||
| Ce/Ut/Mt/Lt/Ae | 0/2/15/10/1 | 0/8/27/23/3 | 0.836b |
| cT category, n | |||
| cT1a + 1b/2/3/4a + 4b | 16/7/5/0 | 25/15/21/0 | 0.235c |
| cN category, n | |||
| cN0/1/2/3/4 | 20/2/3/0/3 | 28/11/18/4/0 | 0.0045b |
| cM category, n | |||
| cM0/1 | 28/0 | 61/0 | >0.999b |
| cStage, n | |||
| cStage 0/1/2/3/4a/4b | 7/6/9/3/3/0 | 6/11/19/25/0/0 | 0.0001b |
| Treatment, n | 0.0597b | ||
| Endoscopic | 6 | 3 | |
| Esophagectomy first | 16 | 39 | |
| NAC + esophagectomy | 6 | 19 | |
| pT category, n | |||
| pT0/1a + 1b/2/3/4a | 3/19/2/4/0 | 4/31/10/15/1 | 0.411b |
| pN category, n | |||
| pN0/1/2/3/4/X | 16/3/4/2/0/3 | 31/7/12/8/1/2 | 0.702b |
| pStage, n | |||
| pStage 0/1/2/3/4a/X | 2/11/5/5/2/3 | 1/18/14/15/9/4 | 0.527b |
a
Student's t-test;
b
Fisher's exact test;
c
χ2 test. Ce, cervical esophagus; Ut, upper thoracic esophagus; Mt, middle thoracic esophagus; Lt, lower thoracic esophagus; Ae, abdominal esophagus; NAC, neoadjuvant chemotherapy.