Table 2.
Association between HbA1c level at the time of diagnosis and advanced fibrosis (fibrosis stage 3–4)
| Variable | HbA1c |
|||
|---|---|---|---|---|
| ≤5.4% | 5.5%–6.4% | 6.5%–7.4% | ≥7.5% | |
| Crude OR (95% CI) | 1.00 | 2.56 (1.15–6.30) P=0.02 | 5.72 (2.36–15.18) P<0.01 | 3.38 (1.44–8.69) P=0.03 |
| Adjusted OR (95% CI) | ||||
| Model 1 | 1.00 | 1.49 (0.59–3.77) P=0.40 | 2.87 (1.05–7.86) P=0.04 | 2.11 (0.80–5.52) P=0.13 |
| Model 2 | 1.00 | 2.63 (1.08–6.37) P=0.03 | 5.33 (2.00–14.19) P<0.01 | 2.65 (1.01–7.00) P=0.049 |
Differences were considered statistically significant at P<0.05. Model 1 was adjusted for age (years), sex, and hemoglobin (g/L), alanine aminotransferase (IU/L), and creatinine (μmol/L) levels. Model 2 was adjusted for body mass index (kg/m2) and uric acid (μmol/L), total cholesterol (mmol/L), and triglyceride (mmol/L) levels.
HbA1c, glycosylated hemoglobin; OR, odds ratio; CI, confidence interval.