Table 3.
Association between HbA1c levels at the time of diagnosis and high NAS (score 5–8)
| Variable | HbA1c |
|||
|---|---|---|---|---|
| ≤5.4% | 5.5%–6.4% | 6.5%–7.4% | ≥7.5% | |
| Crude OR (95% CI) | 1.00 | 4.14 (1.95–9.43) P<0.01 | 4.31 (1.85–10.70) P<0.01 | 4.46 (1.98–10.74) P<0.01 |
| Adjusted OR (95% CI) | ||||
| Model 1 | 1.00 | 3.00 (1.11–8.17) P=0.03 | 3.81 (1.26–11.51) P=0.02 | 4.50 (1.57–12.87) P<0.01 |
| Model 2 | 1.00 | 3.80 (1.68–8.60) P<0.01 | 3.61 (1.43–9.06) P<0.01 | 3.60 (1.44–9.01) P<0.01 |
Differences were considered statistically significant at P<0.05. Model 1 was adjusted for age (years), sex, and hemoglobin (g/L), alanine aminotransferase (U/L), and creatinine (μmol/L) levels. Model 2 was adjusted for body mass index (kg/m2) and uric acid (μmol/L), total cholesterol (mmol/L), and triglyceride (mmol/L) levels.
HbA1c, glycosylated hemoglobin; NAS, NAFLD activity score; OR, odds ratio; CI, confidence interval.