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. 2023 Nov 27;18(5):738–750. doi: 10.1093/ecco-jcc/jjad197

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© The Author(s) 2023. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Treatment targets at 3 months and 2 years in children with Crohn’s disease, stratified by early anti-TNF use. ^aThese outcomes were only evaluated in patients with available faecal calprotectin results. ^bMucosal healing was estimated by the Mucosal Inflammation Noninvasive [MINI] Index. TNF, tumour necrosis factor; C-reactive protein; FCP, faecal calprotectin; NCR, normal CRP remission [remission with CRP <0.5 mg/dl]; NFR, normal FCP remission [remission with faecal calprotectin <250 μg/g]; SSFR*, sustained steroid-free remission without treatment intensification; SSFMI, sustained steroid-free mild or inactive disease; SSFMI*, SSFMI without treatment intensification.