Table 4.

Crude odds ratio and risk ratio of early anti-TNF therapy for sustained steroid-free mild or inactive disease without treatment intensification at one year by paediatric Crohn’s disease risk groups.

Subgroup	OR	95% CI	p-value	RR	95% CI	p-value
Mild/inactive disease at diagnosis	3.86	1.27–11.72	0.02	2.91	0.92–9.11	0.07
Moderate/severe disease at diagnosis	7.22	3.45–15.13	<0.001	5.50	2.51–12.05	<0.001
No POPO	4.63	1.03–20.87	0.046	3.41	0.54–21.7	0.19
Any POPO	6.66	3.48–12.72	<0.001	5.05	2.45–10.43	<0.001

TNF, tumour necrosis factor; OR, odds ratio; CI, confidence interval; RR, relative risk; POPO, predictor of poor outcome.