Table 3.
Significant associations between genetic variability at the different markers of FOXP2, CNTNAP2 and PRNP and MMSE and CDR scores in FTD samples, under an additive model.
| SNP-GENE | Minor Allele | β | P-value |
|---|---|---|---|
| MMSE | |||
| rs10255943-FOXP2 | A | 4.692 | 0.030 |
| rs4727799-FOXP2 | T | −3.694 | 0.025 |
| rs2396752-FOXP2 | C | 6.044 | 0.019 |
| rs7799652-FOXP2 | G | −2.984 | 0.043 |
| rs2972106-CNTNAP2 | A | −3.112 | 0.041 |
| rs2756271-PRNP |
A |
2.673 |
0.046 |
| CDR | |||
| rs17213159-FOXP2 | T | −0.925 | 0.029 |
*MMSE: Mini Mental State Examination CDR: Clinical Dementia Rating scale.