Table 3.
Change in Reservoir Measures since vaccination, N=54 participants and 650 timepoints
| HIV RNAGag | Total HIV DNA | HIV DNA 2LTR | HIV RNATat-Rev | |||||
|---|---|---|---|---|---|---|---|---|
| Fixed Effect | Model Coefficient* (95% CI) |
p-value | Model Coefficient* (95% CI) |
p-value | Model Coefficient* (95% CI) |
p-value | Model Coefficient* (95% CI) |
p-value |
| Days from vaccine to visit | −0.002 (−0.006 to 0.002) |
0.26 | 0.001 (−0.002 to 0.003) |
0.51 | 0.001 (−0.002 to 0.004) |
0.65 | 0.002 (−0.002 to 0.006) |
0.39 |
| Saline | Reference | Reference | Reference | Reference | ||||
| Influenza | 0.10 (−0.02 to 0.22) |
0.12 | 0.11 (0.01 to 0.21) |
0.04 | −0.04 (−0.13 to 0.05) |
0.41 | 0.04 (−0.10 to 0.18) |
0.55 |
| Pneumococcal | −0.02 (−0.14 to 0.11) |
0.80 | 0.08 (−0.03 to 0.19) |
0.13 | −0.07 (−0.16 to 0.02) |
0.13 | <0.001 (−0.140 to 0.141) |
1.00 |
| Level of RNA/DNA on day of vaccination° | −0.76 (−0.86 to −0.66) |
<.01 | −0.32 (−0.41 to −0.24) |
<.01 | −0.70 (−0.80 to −0.60) |
<.01 | −0.92 (−1.03 to −0.82) |
<.01 |
Coefficients estimated from multivariable, mixed-effects linear regression. Coefficients with p<0.05 imply that effects were different than zero,
Corresponds to the day of vaccination for each cycle