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. Author manuscript; available in PMC: 2025 Jul 1.
Published in final edited form as: AIDS. 2024 Mar 22;38(8):1131–1140. doi: 10.1097/QAD.0000000000003882

Table 3.

Change in Reservoir Measures since vaccination, N=54 participants and 650 timepoints

HIV RNAGag Total HIV DNA HIV DNA 2LTR HIV RNATat-Rev
Fixed Effect Model Coefficient*
(95% CI)
p-value Model Coefficient*
(95% CI)
p-value Model Coefficient*
(95% CI)
p-value Model Coefficient*
(95% CI)
p-value
Days from vaccine to visit −0.002
(−0.006 to 0.002)
0.26 0.001
(−0.002 to 0.003)
0.51 0.001
(−0.002 to 0.004)
0.65 0.002
(−0.002 to 0.006)
0.39
Vaccines
 Saline Reference Reference Reference Reference
 Influenza 0.10
(−0.02 to 0.22)
0.12 0.11
(0.01 to 0.21)
0.04 −0.04
(−0.13 to 0.05)
0.41 0.04
(−0.10 to 0.18)
0.55
 Pneumococcal −0.02
(−0.14 to 0.11)
0.80 0.08
(−0.03 to 0.19)
0.13 −0.07
(−0.16 to 0.02)
0.13 <0.001
(−0.140 to 0.141)
1.00
Level of RNA/DNA on day of vaccination° −0.76
(−0.86 to −0.66)
<.01 −0.32
(−0.41 to −0.24)
<.01 −0.70
(−0.80 to −0.60)
<.01 −0.92
(−1.03 to −0.82)
<.01
*

Coefficients estimated from multivariable, mixed-effects linear regression. Coefficients with p<0.05 imply that effects were different than zero,

°

Corresponds to the day of vaccination for each cycle