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Summary of results for the cox mutants
| Protein | Amino acid substition | Tetramerization | Repression | Activation | Excision | DNA binding |
|---|---|---|---|---|---|---|
| Cox | − | +++ | +++ | +++ | +++ | +++ |
| Cox2 | Met42Thr | + | − | − | − | − |
| Cox3 | Gly22Glu | − | n.d. | n.d. | n.d. | n.d. |
| Cox4 | Glu54Lys | − | − | + | + | − |
| Cox107 | Arg29His | − | − | + | + | − |
| Cox129 | Ala69Thr | − | − | + | + | − |
| Cox130 | Glu16Lys | +++ | ++ | ++ | ++ | ++++ |
−, no activity; +++, wild-type activity; n.d., not determined due to the formation of inclusion bodies.
