Table 1.
Clinical Characteristics of Cases with Escherichia Coli or Klebsiella Pneumoniae Bacteremia
| General and Clinical Characteristics | N=61 |
|---|---|
| Age years, median (range) | 54 (31.5,63.5) |
| Gender male/female | 40 (65.6) |
| Klebsiella pneumoniae bacteremia | 22 (36.1) |
| Escherichia coli bacteremia | 39 (63.9) |
| Underlying hematological disorders | |
| Acute leukemia | 16 |
| Chronic myelomonocytic leukemia (CMML) | 1 |
| Multiple myeloma/plasma cell leukemia | 5 |
| Aggressive lymphoma | 39 |
| No. of previous chemotherapy lines | 5 (2–8) |
| Evaluation of the effectiveness of previous chemotherapy | |
| Untreated | 8 |
| Relapse/refractory | 22 |
| Partial remission | 5 |
| Complete remission | 22 |
| Stable disease | 2 |
| Not evaluated | 2 |
| Comorbidities | |
| Coronary heart disease | 3 |
| Diabetes mellitus | 5 |
| Arrhythmia | 3 |
| Peptic ulcer | 2 |
| Interstitial lung disease | 4 |
| Invasive pulmonary fungal disease | 5 |
| Autogenetic peripheral blood stem cell transplantation | 12 (19.7) |
| Allogeneic hematopoietic stem cell transplantation | 6 (9.8%) |
| Systemic corticosteroids | 22 (36.1) |
| Central venous catheter insertion | 18 (29.5) |
| Peripheral catheter insertion | 39 (63.9) |
| GI tract or perianal infection | 26 (42.6) |
| Fever °C degree, median (range) when BSI onset | 39.5 (37–42) |
| ANC < 500 (cells/mm3) when BSI onset | 49 (80.3) |
| ANC < 100 (cells/mm3) when BSI onset | 47 (77.0) |
| Days of ANC < 500 (cells/mm3) | 9 (5–13) |
| Initial empirical application of carbapenems | 59 (96.7) |
| CRE | 10 (16.4) |
| Septic shock | 14 (23.0) |
| Mechanical ventilation | 4 (6.5) |
| Overall 28-day mortality | 12 (19.7) |
Abbreviation: GI, gastrointestinal.