Table 3.
Clinical Characteristics of Early Response and Risk Factors for CRE
| Resistant Group (n=10) | Susceptible Group (n=51) | χ2/Z value | P value | Multivariate Regression | ||
|---|---|---|---|---|---|---|
| OR | P value | |||||
| Age, years | 61.5 (47–66) | 51.0 (31–62) | −1.277 | 0.202 | ||
| Male | 7 | 33 | 0.104 | 1.000 | ||
| K. pneumoniae | 7 | 15 | 5.973 | 0.027 | ||
| Escherichia coli | 3 | 36 | ||||
| GI or perianal infection | 4 | 22 | 0.034 | 1.000 | ||
| HSCT | 2 | 16 | 0.52 | 0.732 | ||
| K. pneumoniae in HSCT | 2 | 1 | 1.94 | 0.467 | ||
| Escherichia coli in HSCT | 0 | 15 | 2.03 | 0.419 | ||
| Peak temperature on d3 | 39.0 (38.3–39.6) | 37 (36.6–37.8) | −3.769 | <0.001 | 3.325 (1.084–9.592) | 0.035 |
| Impaired mental status | 8 | 3 | 31.07 | <0.001 | 6.117 (3.149–16.630) | 0.003 |
| Septic shock within 72h of onset of BSI | 7 | 7 | 14.97 | <0.001 | ||
| Mechanical ventilation | 4 | 0 | 21.83 | <0.001 | ||
| Pitt score | 5 (2.8–6.0) | 1 (0.0–2.0) | −3.645 | <0.001 | ||
| PCT on d3 | 23.29 (6.72–32.58) | 0.75 (0.23–2.68) | 71.0 | <0.001 | ||
| Time to first positive by sterility blood culture (hours) | 9.1 (5.7–12.1) | 8.8 (7.3–10.6) | −0.214 | 0.830 | ||
| Time to get susceptibility reports (days) | 3.0 (3.0–5.0) | 3.0 (2.0–4.0) | −0.475 | 0.635 | ||