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The location and number of STAT5B mutations. In total, 83 mutations were identified in 82 patients. One patient with chronic eosinophilic leukemia, not otherwise specified had two concurrent mutations, Y665F and D428N. STAT5B mutations clustered in the SH2 domain in 78 (95%) cases and were missense mutations in all cases, with N642H being the most common, seen in 64 (78%) cases. aa: amino acids. (Note: the number of amino acids on the X-axis is not proportionally scaled).
