Fig. 8. In vivo biosafety evaluation of chemo-SDT based on DH-HM@BSA. (a) H&E staining images of the main organs dissected from the mice of various groups on day 16 after various treatments (scale bars are 50 μm). (b) Hematological tests, such as regular blood indicators (WBC, PLT, PMN, LYM) and functions of liver and kidney (ALT, AST, CREA, BUN), of different groups on day 16 after various treatments. The date are expressed as means ± SD (n = 3) (***p < 0.001, **p < 0.01, and *p < 0.05).