Skip to main content
[Preprint]. 2024 May 25:2024.03.31.587283. [Version 2] doi: 10.1101/2024.03.31.587283

Figure 4: gRNAde compared to Rosetta for single-state design.

Figure 4:

(a) We benchmark native sequence recovery of gRNAde, Rosetta, FARNA and ViennaRNA on 14 RNA structures of interest identified by Das et al. [2010]. gRNAde obtains higher native sequence recovery rates (56% on average) compared to Rosetta (45%). (b) Sequence recovery per sample for Rosetta and gRNAde, shaded by gRNAde’s perplexity for each sample. gRNAde’s perplexity is correlated with native sequence recovery for designed sequences. Full results are available in Appendix Table 2.