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[Preprint]. 2024 May 26:2024.05.22.595431. [Version 1] doi: 10.1101/2024.05.22.595431

Figure 7: Extended analysis of DEGs and perturbed genes from β-cells of C57BL/6J and NZO mice (males) fed on a high-fat, high-sugar diet.

Figure 7:

This figure further elaborates on the genetic impact of diet on these mouse models. (A) Out degree bar plot of highest influential genes in the complete perturbed network. (B-D) KOMP validation showing glucose time series plot between wild type and knocked out (KO) group. (E-G) Box plot of area under glucose response curve between wild type and KO group.