TABLE 1.
Relevant properties of some of the strains analyzed
| Strain | Serotype | PFGE type | Penicillin MIC (μg/ml) | Susceptibility (S) or resistance (R)
|
No. of kb of SmaI hybridization pattern
|
murM allele | Cell wall composition | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Erythro mycin | Tetracycline | Chloramphen- icol | Sulfamethoxazole-trimethoprim | lytA |
murM probe
|
||||||||||
| MurMAI | MurMBI | ||||||||||||||
| Hun663 | 19A | Hun 1A | 2 | R | R | R | NDa | ND | 95 | murMB1 | Abnormally high Ala-Ala | ||||
| Hun524 | 19A | Hun 1A | 2 | R | R | R | R | 280/95 | 95 | murMB1 | Abnormally high Ala-Ala | ||||
| Hun45 | 19 | Hun 1A | 16 | R | R | R | R | 280/95 | 95 | murMB1 | Abnormally high Ala-Ala | ||||
| 8249 | 19A | SA1 | 6 | R | R | R | ND | ND | ND | ND | murMB2 | Abnormally high Ala-Ala/Ala-Ser | |||
| D20 | 19A | SA1 | 12 | R | R | R | ND | ND | ND | ND | murMB2 | Abnormally high Ala-Ala/Ala-Ser | |||
| CA 39 | 6 | 12 | 1.5 | S | S | S | I | >450/80 | 95 | murMB8 | Abnormally high Ala-Ala | ||||
| KY 4 | 23 | USA 5 | 2 | S | S | S | I | 260/85 | 95 | 95 | murMB4 | Abnormally high Ala-Ala/Ala-Ser | |||
| KY 5 | 23 | USA 5 | 3 | S | S | S | I | 260/85 | 95 | 95 | murMB4 | ND | |||
| KS 11 | 23 | USA 5 | 4 | S | S | S | R | 260/85 | 95 | murMA | ND | ||||
| WA2 | 23 | USA 5 | 0.023 | S | S | S | S | 85/70 | 95 | murMA | ND | ||||
| KY 17 | NTb | 30 | 1.5 | R | R | S | R | 450/160/60 | 450 | 450 | murMB5 | Abnormally high Ala-Ser | |||
| DE 1 | 14 | USA 22 | 3 | S | S | S | S | 85 | 95 | murMB3 | Abnormally high Ala-Ala | ||||
| SD 3 | 14 | USA 22 | 4 | R | S | S | R | 85 | 95 | murMA | ND | ||||
| MD1 | 14 | USA 22 | 0.05 | R | S | S | R | 85 | 95 | murMA | ND | ||||
| NE 6 | 6 | USA 10 | 6 | R | R | S | R | 360/100/50 | 95 | 95 | murMB7 | ND | |||
| FL10 | 6 | USA 10 | 2 | R | R | R | R | 360/85 | 95 | murMA | ND | ||||
| WI 3 | 6 | USA 10 | 4 | R | R | R | I | 360/100/50 | 95 | murMA | ND | ||||
| TX 6 | 6 | USA 17 | 6 | R | S | S | R | 105/60 | 95 | murMB6 | ND | ||||
| TX 7 | 6 | 14 | 4 | R | S | S | R | 105 | 95 | murMB6 | ND | ||||
| VP145 | 23 | A | 0.5 | ND | ND | ND | ND | 225/90/30 | 95 | murMA | Normal | ||||
| Sp2150 | 14 | B | 1 | S | S | S | ND | 260/95 | 50 | murMA | Normal, R6Hex | ||||
| TX 3 | 9 | B | 2 | S | S | S | I | 260/130 | 50 | murMA | ND | ||||
| Bul125 | 9 | B | 4 | S | S | S | R | 260/95 | 50 | murMA | Normal, R6Hex | ||||
| TX26 | 6 | USA 20 | 3 | S | S | S | S | 85 | 60 | murMA | ND | ||||
| CA3 | 19 | USA 3 | 3 | R | R | S | R | 115 | 90 | murMA | ND | ||||
| TX 4 | 19 | USA 3 | 2 | R | R | S | R | 115 | 90 | NSc | ND | ||||
| TX 5 | 14 | USA 16 | 6 | R | R | S | R | 95/40 | 95 | NS | ND | ||||
| GA 30 | NT | USA 16 | 8 | R | R | S | R | 95/40 | 95 | NS | ND | ||||
| GA12 | 14 | USA 16 | 4 | R | R | S | R | 95/70 | 95 | NS | ND | ||||
| OH 4 | 6 | USA 9 | 2 | R | S | S | R | 100/60 | 380 | NS | ND | ||||
| OH 11 | 6 | USA 9 | 2 | R | S | S | R | 100/60 | 380 | NS | ND | ||||
| OH 13 | 6 | USA 9 | 2 | R | S | S | R | 100/60 | 380 | NS | ND | ||||
| UT 1 | 19 | UT 20 | 0.008 | S | ND | ND | S | 280/95 | 100 | NS | ND | ||||
| UT 5 | 19 | UT 20 | 0.016 | S | ND | ND | S | 280/95 | 100 | NS | ND | ||||
| UT 41 | 11 | USA 27 | 0.016 | S | ND | ND | S | 85 | 300 | NS | ND | ||||
| UT 126 | 11 | USA 27 | 0.008 | S | ND | ND | S | 85 | 300 | NS | ND | ||||
| UT 67 | NT | USA 39 | 0.016 | S | ND | ND | S | 95 | 350 | NS | ND | ||||
| UT 91 | NT | USA 39 | 0.008 | S | ND | ND | S | 95 | 350 | NS | ND | ||||
a
ND, not done.
b
NT, nontypeable.
c
NS, not sequenced.