Table 2. Delays to first treatment (Dt) and to surgery (Ds) and pandemic measurements.

	Date of diagnosis
	Before&After 1st lockd. start (All)	Before 1st lockd. start	After 1st lockd. start
	N of days	N of days	N of days	p-value
Delay to first therapy
W/ and w/o NACT* (All)	N = 187	N = 99	N = 88
Mean (SD)	45.3 (21.78)	44.7 (18.31)	46 (25.21)
Median (IRQ)	42 (32–54)	42 (32–54)	42.5 (33–54)	0.82**
Range	7–208	11–106	7–208
Delay to surgery
Patients w/o NACT	N = 110	N = 55	N = 55
Mean (SD)	43.7 (20.2)	43.1 (19.91)	44.3 (20.65)
Median (IRQ)	39.5 (30–53)	37 (31–51)	45 (29–54)	0.55**
Range	7–106	11–106	7–104
Patients w/ NACT	N = 77	N = 44	N = 33
Mean (SD)	74.3 (28.17)	72.3 (24.18)	77 (32.95)
Median (IRQ)	69 (60–86)	65 (56–87)	70 (63–85)	0.59**
Range	24–232	24–124	39–232
Composite Pandemic Indicator
All patients	N = 187	N = 99	N = 88
Mean (SD)	69.7 (93.07)	22.4 (34.49)	122.9 (108.5)
Median (IRQ)	30.7 (0.1–101.0)	3.4 (0–28.6)	93.1 (33.3–177.2)
Range	69.7–93.07	0–155.7	6.5–573.1
Nantes center	N = 34	N = 21	N = 13	<0.001***
Mean (SD)	28 (37.5)	10.7 (15.59)	55.8 (45.9)
Median (IRQ)	18.6 (0–44.3)	0 (0–18.8)	46.8 (19.9–78.7)
Range	0–177.6	0–58.8	6.5–177.6
Angers center	N = 66	N = 39	N = 27
Mean (SD)	58.9 (65.68)	19.8 (28)	115.2 (63.69)
Median (IRQ)	43.1 (0–91.62)	0.1 (0–42.5)	100.2 (76.7–139.1)
Range	0–286.3	0–116.3	24.2–286.3
Clermont-Ferrand center	N = 36	N = 11	N = 25
Mean (SD)	68.6 (92.18)	7.4 (7.36)	95.5 (99.51)
Median (IRQ)	13.6 (9.7–119.9)	6.9 (0–12.5)	32.7 (11.4–161.4)
Range	0–298.8	0–20.7	9.5–298.8
Nancy center	N = 51	N = 28	N = 23
Mean (SD)	112.2 (128.67)	40.5 (49.66)	199.5 (141.78)
Median (IRQ)	70.9 (0–155.7)	13.8 (0–77.0)	176.7 (91.9–303.3)
Range	0–574.1	0–155	33–573.1

*NACT–Neoadjuvant Chemotherapy;

**Wilcoxon rank-sum test comparing before and after the start of the 1^st lockdown for the delay to first treatment and the delay to surgery;

***Wilcoxon rank-sum test comparing the composite pandemic index between centers for patients diagnosed after the start of the 1^st lockdown (N = 88)