Table 3.

First 20 pathways based on P value for upregulated genes

Symbol	Pathway
KDM4B	Histone demethylases demethylate histones
NOTCH4	Pre-NOTCH transcription and translation
NOTCH4	Pre-NOTCH expression and processing
IGHM	Classical antibody-mediated complement activation
IGHM	Fc-gamma receptor (FCGR) activation
IGHM	Creation of C4 and C2 activators
IGHM	Initial triggering of complement
IGHM	Role of phospholipids in phagocytosis
IGHM	Complement cascade
IGHM	Regulation of actin dynamics for phagocytic cup formation
KDM4B	Chromatin-modifying enzymes
KDM4B	Chromatin organization
PANX2	Transmission across electrical synapses
PANX2	Electric transmission across gap junctions
IGHM	FCGR-dependent phagocytosis
COL27A1 COL18A1	Assembly of collagen fibrils and other multimeric structures
NOTCH4	Signaling by NOTCH
PGF	Vascular endothelial growth factor（VEGF）ligand-receptor interactions
PGF	VEGF binds to VEGF receptor leading to receptor dimerization
COL27A1 COL18A1	Collagen biosynthesis and modifying enzymes