Table 1. Maternal–fetal evaluations since the beginning of the pregnancy.

GA	6 wk	12 + 4 wk	18 + 3 W	22 + 4 wk	24 + 3 wk	27 + 4 wk	30 + 2 wk	33 wk	33 + 6 wk	Normal reference ranges
TSH	0.291	0.524	1.2	0.22	0.015	0.02	0.0011			0.3–4.2 µUI/mL
FT4	1.3	1.31	1.3	1.09	1.33	0.9	1.26			0.7–1.48 ng/dL
T4	10.3	9.81	10	11.4	12.9	11.2	10			<16 wk: 5.5–11.5 µg/dL >16 wk: 8.25–15.25 µg/dL
TRAb s	21.3		16.4		18.7 (TSI)					< 0.1 U/L
Treatment	LT4 150 µg	LT4 150 µg	LT4 150 µg	LT4 150 µg Methimazole 10 mg	LT4 150 µg Methimazole 15 mg	LT4 150 µg Thiamazole 20 mg	LT4 150 µg Methimazole 20 mg		Preterm labor
Fetal US		HR: 153 × min AF normal		Fetal tachycardia, goiter with central hypervascularization. Long bones >p90	Sinus tachycardia, goiter improvement	Fetal tachycardia, goiter, exophthalmos	Similar goiter, normocardia, exophthalmos	Suspected craniosynostosis, HR: 160 × min
Mother's physical examination						Exophthalmos, HR: 95 × min tremor (+)

Abbreviations: AF, amniotic fluid; FT4, free thyroxine; GA, gestational age; HR, heart rate; LT4, levothyroxine; T4, thyroxine; TRAbs, thyrotropin receptor antibodies; TSH, thyroid-stimulating hormone; TSI, thyroid-stimulating immunoglobulin.