Figure 1.

H&E-stained section of liver cores showing azonal sinusoidal dilatation and zone 3 bland cholestasis without significant portal or lobular inflammation or portal bile ductular proliferation. (a-b) Different areas of the core to show diffuse azonal sinusoidal dilatation. (b) Focal peliosis hepatis (cystically dilated spaces communicating with the sinusoids). (c) A high magnification view of the boxed zone 3 area in A showing marked canalicular cholestasis. Bland cholestasis and sinusoidal dilatation/peliosis in isolation are often due to medications and when present together are highly suggestive of anabolic steroid use.