Table 1.

Distribution of risk factors among included studies

Risk factor	Total number of analyses in all studies	Studies including analyses of risk factorsa
Cancer	20	[45, 49, 51, 52, 57, 86, 89, 93, 103]
Diabetes	17	[13, 38, 41, 45, 49, 51, 52, 56, 59, 73, 82, 92, 94, 99, 100, 103]
Autoimmune disorders	16	[40, 45, 49, 51, 52, 77, 86, 90, 92, 103]
Mental health condition	15	[38, 44, 74, 85, 106, 109, 110, 113, 114]
Musculoskeletal disorders	14	[51, 52, 81, 86, 95–97, 99, 103, 107]
RA	13	[13, 49, 51, 52, 69, 80, 86, 88, 89, 92]
HIV	12	[37, 45–47, 63, 71, 82, 86, 89, 92, 94, 103]
Asthma	11	[13, 43, 45, 51, 52, 68, 92, 101–103, 112]
Cardiovascular disorders	11	[13, 45, 49, 51, 52, 99, 103, 111]
Digestive disorders	11	[38, 53, 55, 58, 61, 65, 72, 90, 103]
COPD	10	[13, 45, 51, 52, 67, 75, 85, 92, 99, 103],
Transplantation	10	[36, 48, 51, 52, 82, 86, 89, 92]
SLE	10	[39, 42, 49, 51, 52, 66, 69, 86, 89, 92]
Renal disorders	10	[49, 51, 52, 62, 84, 86, 87, 92, 104, 105]
Depression	9	[13, 51, 52, 91, 92, 99, 106, 109, 110]
Endocrine and metabolic disorders	8	[50–52, 86, 99]
IBD	8	[51, 52, 55, 64, 72, 86, 89, 92]
CHF	7	[13, 45, 51, 52, 83, 103, 111]
Hematological disorders	7	[60, 92, 94, 98]
Neurological disorders	6	[51, 52, 54, 78, 79, 103]
Psoriasis	6	[51, 52, 76, 86, 89, 108]

RA, rheumatoid arthritis; COPD, chronic obstructive pulmonary disorder; SLE, systemic lupus erythematosus; IBD, inflammatory bowel disease; CHF, chronic heart failure

^aPlease note that a single study may include both analyses of multiple risk factors and multiple analyses of the same risk factor