Table 2.
Baseline echocardiographic characteristics of the patients and predictors of the composite outcome in chronic Chagas cardiomyopathy
| Variables | Patients without CO events (n = 137) | Patients with CO events (n = 40) | HR (95% CI) | p-Value | |
|---|---|---|---|---|---|
| LVEF (%) | 50 (38; 59) | 28 (19; 36) | 0.92 (0.89–0.94) | < 0.001 | |
| LVEF (%) | |||||
| ≥ 40 | 98 (71.53) | 7 (17.50) | Reference | ||
| < 40 | 39 (28.47) | 33 (82.50) | 8.75 (3.86–19.81) | < 0.001 | |
| End-diastolic volume, ml | 60 (47; 83) | 98 (69; 151) | 1.02 (1.01–1.02) | < 0.001 | |
| End-systolic volume, ml | 32 (21; 50) | 68 (44; 119) | 1.02 (1.01–1.03) | < 0.001 | |
| LV Mass Index | 106 (83; 133) | 151 (117; 185) | 1.01 (1.01–1.02) | < 0.001 | |
| LV aneurysms | 23 (16.79) | 10 (26.32) | 1.46 (0.71–3.00) | 0.308 | |
| LA Volume Index, ml/m2 | 39 (29; 52) | 67 (53; 88) | 1.02 (1.01–1.03) | < 0.001 | |
| Lateral e, cm/s | 9 (6; 12) | 6 (5; 9) | 0.83 (0.74–0.94) | 0.003 | |
| Lateral a, cm/s | 10 (8; 13) | 7 (5; 10) | 0.75 (0.67–0.84) | < 0.001 | |
| E/e′ ratio | 7.35 (5; 9) | 10.05 (8; 14) | 1.16 (1.08–1.23) | < 0.001 | |
| TAPSE | 18 (15; 21) | 12 (10; 15) | 0.81 (0.75–0.87) | < 0.001 | |
| MAPSE | 10 (8; 13) | 7 (5; 9) | 0.81 (0.73–0.89) | < 0.001 | |
| PASP | 30 (26; 34) | 38 (31; 50) | 1.07 (1.05–1.10) | < 0.001 | |
This table contains % for categorical variables and median (first and third quartile) for continuous variables
LVEF left ventricle ejection fraction, PSAP pulmonary artery systolic pressure
Bold values indicate a p-value < 0.05