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. 2024 May 31;13:49. doi: 10.1186/s13741-024-00403-w

Table 2.

Frequency (%) of surgeries that had at least one prescription for each medication and drug class

Hip replacement (n = 558) Knee replacement (n = 724) Total (n = 1282)
Opioids 557 (99.8) 724 (100) 1281 (99.9)
 Oxycodone 488 (87.5) 631 (87.2) 1119 (87.3)
 Tapentadol 322 (57.7) 479 (66.2) 801 (62.5)
 Fentanyl 152 (27.2) 182 (25.1) 334 (26.1)
 Morphine 166 (29.8) 167 (23.1) 333 (26)
 Buprenorphine 122 (21.9) 210 (29) 332 (25.9)
 Tramadol 83 (14.9) 68 (9.4) 151 (11.8)
 Oxycodone-naloxone 74 (13.3) 52 (7.2) 126 (9.8)
 Hydromorphone 25 (4.5) 13 (1.8) 38 (3)
 Codeine 4 (0.7) 0 4 (0.3)
Paracetamol 556 (99.6) 723 (99.9) 1279 (99.8)
 Paracetamol 556 (99.6) 723 (99.9) 1279 (99.8)
Nonsteroidal anti-inflammatories 106 (19) 138 (19.1) 244 (19)
 Aspirin (dose ≥ 150 mg/day) 37 (6.6) 67 (9.3) 104 (8.1)
 Celecoxib 37 (6.6) 46 (6.4) 83 (6.5)
 Ibuprofen 12 (2.2) 14 (1.9) 26 (2)
 Diclofenac 9 (1.6) 7 (1) 16 (1.3)
 Indomethacin 5 (0.9) 2 (0.3) 7 (0.6)
 Parecoxib 4 (0.7) 3 (0.4) 7 (0.6)
 Naproxen 4 (0.7) 2 (0.3) 6 (0.5)
 Ketoprofen 2 (0.4) 0 2 (0.2)
 Ketorolac 1 (0.2) 1 (0.1) 2 (0.2)
 Piroxicam 0 1 (0.1) 1 (0.1)
Antiepileptics 64 (11.5) 91 (12.6) 155 (12.1)
 Pregabalin 53 (9.5) 80 (11.1) 133 (10.4)
 Gabapentin 8 (1.4) 8 (1.1) 16 (1.3)
 Carbamazepine 3 (0.5) 5 (0.7) 8 (0.6)
 Topiramate 0 2 (0.3) 2 (0.2)
Corticosteroids 65 (11.7) 52 (7.2) 117 (9.1)
Dexamethasone 39 (7) 30 (4.1) 69 (5.4)
 Prednisolone 24 (4.3) 20 (2.8) 44 (3.4)
 Hydrocortisone 6 (1.1) 6 (0.8) 12 (0.9)
 Methylprednisolone 1 (0.2) 0 1 (0.1)
Antidepressants 40 (7.2) 65 (9) 105 (8.2)
 Amitriptyline 27 (4.8) 30 (4.1) 57 (4.5)
 Venlafaxine 8 (1.4) 20 (2.8) 28 (2.2)
 Duloxetine 7 (1.3) 15 (2.1) 22 (1.7)
Anaesthetics 7 (1.3) 10 (1.4) 17 (1.3)
 Ketamine 7 (1.3) 10 (1.4) 17 (1.3)
Muscle relaxants 2 (0.4) 0 2 (0.2)
 Baclofen 2 (0.4) 0 2 (0.2)

Values may not add up to 100% due to rounding