Table 3.

All-cause mortality at 6, 12, and 24 months of follow-up, stratified by number of rCDIs

Time	Statistical parameters	All CDI patients	Patients with no rCDI	Patients with 1 rCDI	Patients with 2 rCDIs	Patients with ≥ 3 rCDIs	Patients with ≥ 1 rCDIs
Death at 6 months	Number of patients at index	9,977	8,175	1,356	312	134	1,802
	Number of deaths	3,242	2,674	439	99	30	568
	6-month mortality rate (%)	32.49	32.71	32.37	31.73	22.39	31.52
	95% CI for proportion	[31.58; 33.41]	[31.69; 33.73]	[29.88; 34.87]	[26.57; 36.90]	[15.33; 29.45]	[29.38; 33.67]
Death at 12 months	Number of patients at index	9,977	8,175	1,356	312	134	1,802
	Number of deaths	3,896	3,203	522	125	46	693
	12-month mortality rate (%)	39.05	39.18	38.50	40.06	34.33	38.46
	95% CI for proportion	[38.09; 40.01]	[38.12; 40.24]	[35.91; 41.09]	[34.63; 45.50]	[26.29; 42.37]	[36.21; 40.70]
Death at 24 months	Number of patients at indexa	7,729	6,317	1,060	248	104	1,412
	Number of deaths	3,679	3,000	506	125	48	679
	24-month mortality rate (%)	47.60	47.49	47.74	50.4	46.15	48.09
	95% CI for proportion	[46.49; 48.71]	[46.26; 48.72]	[44.73; 50.74]	[44.18; 56.63]	[36.57; 55.73]	[45.48; 50.69]

CDI: Clostridioides difficile infection; rCDI, recurrent CDI infection; CI, confidence interval

^aDeath at 24 months restricted to patients with a potential follow-up of at least 24 months