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. 2024 May 31;14:20451253241255487. doi: 10.1177/20451253241255487

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© The Author(s), 2024

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Clozapine and norclozapine levels in time.

Arrow 0: ‘baseline’ plasma levels on clozapine 600 mg once daily + valproic acid; arrow 1: addition of fluvoxamine 25 mg, clozapine dose adjusted to 500 mg once daily; arrow 2: valproic acid replaced by carbamazepine; arrow 3: clozapine dose increased to 550 mg once daily, fluvoxamine dose increased to 50 mg; arrow 4: admission to hospital, diagnosed with paralytic ileus; after discharge clozapine dose decreased to 450 mg once daily and carbamazepine dose increased; arrow 5: readmission to hospital with suspected paralytic ileus.