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TABLE 2.

Chimeric capsid protein constructsa

Virus Domain exchanged Viable virus recovery
U/NE NADC E region Yes
U/KE KCD E region Yes
U/CE CFI E region No
U/NEL NADC N terminus of E region URB C terminus of E region Yes
U/NER URB N terminus of E region NADC C terminus of E region Yes
U/KEL KCD N terminus of E region URB C terminus of E region No
U/KER URB N terminus of E region KCD C terminus of E region No
U/CEL CFI N terminus of E region URB C terminus of E region Yes
U/CER URB N terminus of E region CFI C terminus of E region No
U/NCDE NADC C, D, and E regions Yes
a

The E region includes amino acid residues 426 through 521; the N terminus of the E region includes amino acid residues 426 through 470; the C terminus of the E region includes amino acid residues 471 through 521; the C, D, and E regions include amino acid residues 397 through 521. Subscripts L and R in virus names represent left and right, respectively.