Fig. 9.

Antioxidant enzyme activities in wild-type and PRLR-null mouse astrocytes. Mouse cortical astrocytes derived from wild-type (Prlr^+/+) or PRLR-null (Prlr^−/−) mice were pre-incubated for 24 h in the absence or presence of 1 nM prolactin (PRL), then 400 μM hydrogen peroxide (H₂O₂) or vehicle (Veh) was added and incubated for 3 h. a Superoxide dismutase (SOD) and b glutathione peroxidase (GPX) activities were detected using the corresponding commercial assay. Data are means ± SEM of three independent experiments (n = 3). One-way ANOVA followed by Tukey’s test. *p < 0.05, **p < 0.001 versus indicated group; n.s., no significant difference