Table 1.
Clinical, laboratory, and demographic data of non-obese and obese patients.
| Non-obese | Obese | |
|---|---|---|
| Demographics | ||
| Number | 5 | 5 |
| Age (years) | 60.4 ± 7.2 | 56.6 ± 9.5 |
| Sex (Male/Female) | 2/3 | 2/3 |
| Body Mass Index (kg/m²) | 24.8 (24.3–26.8) | 45.9 (39.4–48.3)* |
| Related laboratory measures: | ||
| Systolic blood pressure (mmHg) | 115.8 ± 20.2 | 118.0 ± 13.2 |
| Diastolic blood pressure (mmHg) | 65.8 ± 11.2 | 78.2 ± 5.7 |
| Mean blood pressure (mmHg) | 82.4 ± 12.6 | 91.5 ± 7.9 |
| Total cholesterol (mg/dL) | 198.3 ± 25.4 | 209.5 ± 7.8 |
| Triglycerides (mg/dL) | 73.6 ± 8.3 | 111.5 ± 10.6* |
| HDL (mg/dL) | 55.3 ± 16.7 | 52.5 ± 2.1 |
| LDL (mg/dL) | 128.3 ± 8.7 | 125.5 ± 4.9 |
| Fasting glucose (mg/dL) | 92.0 (83.0–118.5) | 96.0 (89.0–137.5) |
| HbA1c (mmol/mol) | 4.9 ± 0.4 | 5.2 ± 0.3 |
| AST (IU/L) | 25.0 ± 2.6 | 22.3 ± 2.1 |
| Uric acid (mg/dL) | 5.0 ± 2.2 | 3.9 ± 2.2 |
| Serum creatinine (mg/dl) | 0.8 ± 1.3 | 0.9 ± 1.4 |
| eGFR-MDRD (ml/min/1.73/m2) | 75.8 ± 15.1 | 78.0 ± 11.0 |
| Proteinuria (mg/24 h) | 185.4 ± 83.2 | 259.5 ± 68.6 |
| Concomitant medication (n/%): | ||
| Antihypertensive drugs | 1/10 | 2/20 |
| Diuretic | 0/0 | 0/0 |
| Statins/lipid-lowering drugs | 0/0 | 0/0 |
| Insulin/oral hypoglycemics | 0/0 | 3/30* |
| Antidepressants/antianxiety | 0/0 | 3/30* |
| Antibiotics | 0/0 | 1/10 |
| Multivitamin | 1/10 | 1/10 |
HDL high-density lipoprotein, LDL low-density lipoprotein, HbA1c A hemoglobin A1c, AST
aspartate aminotransferase, eGFR estimated glomerular filtration rate.
*p ≤ 0.05 vs. non-obese.