Table 2.
Mitochondria-related genes that were upregulated with hyper-hydroxymethylated peaks, or downregulated with hypo-hydroxymethylated peaks, in Obese-MSCs versus Non-obese-MSCs.
| Gene symbol | Gene name | Cellular function |
|---|---|---|
| Upregulated/hyper-hydroxymethylated: | ||
| SLC25A4 | Solute Carrier Family 25 Member 4 | ATP synthesis |
| SLC22A4 | Solute Carrier Family 22 Member 4 | ATP-dependent transport |
| COQ10B | Coenzyme Q10B | Proliferation/Redox activity |
| LAMC1 | Laminin Subunit Gamma 1 | Proliferation/migration |
| Downregulated/hypo-hydroxymethylated: | ||
| COASY | Coenzyme A Synthase | Neurogenic differentiation |
| ECI1 | Enoyl-CoA Delta Isomerase 1 | Fatty acid metabolism |
| MECR | Mitochondrial Trans-2-Enoyl-CoA Reductase | Fatty acid metabolism |