Figure 7.

Subcluster analysis demonstrated heterogeneity of synovial endothelial cell (EC) population in the integrated synovial single-cell map dataset from 25 fresh-dissociated synovial biopsies of patients with inflammatory arthritis

(A) UMAP of eight synovial EC clusters colored by EC cluster.

(B) Bar plots of relative abundances of eight EC clusters across 25 synovial samples colored by EC cluster.

(C) The proportion of the eight EC clusters across 25 synovial tissue samples from patients with inflammatory arthritis. The boxplot visualises five summary statistics: the median; two hinges, corresponding to the first and third quartiles; two whiskers. The upper (lower) whisker extends from the hinge to the largest (smallest) value no further than 1.5 ∗ inter-quartile range from the hinge. Individual dost represent data from different samples.

See also Figures S8–S10, S16, and S17.