Table 1.

Overview of adipokines in relation to the reported main action in osteoarthritis.

Adipokine	Main action in OA	Reference
Leptin	Pro-inflammatory	(13–33) (34–42),
Adiponectin	Anti-inflammatory	(12–15, 17, 18, 21, 24–26, 34–40)
Visvatin	Catabolic	(13–15, 17, 18, 21, 39)
Resistin	Catabolic	(13–15, 18, 21, 24, 25, 35, 38)
Progranulin	Anti-inflammatory	(14, 15)
Chemerin	Pro-inflammatory	(14, 15, 17)
Lipocalin-2	Immunomodulatory	(14, 15)
Vaspin	Immunomodulatory	(14, 15)
Omentin-1	Anti-inflammatory	(14, 15)
Nesfatin	Pro-inflammatory	(14, 15)