FIGURE 7.

Remodelin's Effect on NSCLC Inhibition via NAT10 in Vivo. (A) Images displaying subcutaneous xenograft tumors (n = 6 for each group) derived from A549 cells under various treatment conditions. (B) Images of excised tumors from six BALB/c nude mice at 29 days after various treatment conditions. (C) Hematoxylin and eosin (HE) staining alongside Immunohistochemistry (IHC) of xenograft tumors, depicting the expression levels of Ki67 and Vimentin. (D, E) Evaluation of tumor volumes measured every 4 days and analysis of tumor weights in different experimental groups. (F, G) Examination of NAT10, E‐cadherin, N‐cadherin, and vimentin expression in xenograft tumors using both qRT‐PCR and western blotting techniques. β‐Actin served as the reference gene for qRT‐PCR, while GAPDH acted as the loading control in western blotting. Values represented as mean ± SD from three independent experiments. Statistical analysis conducted using Student's t‐test.