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Fa-PCD/pCKb11/iPD-L1 increased CKb11, IFN-γ and TNF-α expression in vivo. Mice-bearing tumors were treated for 42 days. Then mice were sacrificed and their blood, ascites and tumors were collected. (A) CKb11, (B) IFN-γ and (C) TNF-α levels in tumor, ascites and serum. (D) CKb11 level in different organs by Elisa. (n = 6, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n. s. , no significance; One-way ANOVA).
