Table 3. Physiological indices of microvascular function according to the different age groups of patients with and without CMD.
| No CMD (n=184) | CMD (n=121) | |||||||
|---|---|---|---|---|---|---|---|---|
| Young (n=48) | Intermediate (n=93) | Elderly (n=43) | p-value | Young (n=28) | Intermediate (n=57) | Elderly (n=36) | p-value | |
| Age, years | 47 (6) | 59 (3) | 69 (4) | 0.001 | 47 (4) | 59 (3) | 70 (4) | 0.001 |
| Qrest, mL/min | 74 (23) | 74 (24) | 69 (24) | 0.40 | 113 (35) | 99 (41) | 105 (42) | 0.46 |
| Qmax, mL/min | 224 (87) | 228 (88) | 212 (83) | 0.18 | 199 (55) | 178 (67) | 186 (75) | 0.49 |
| CFR | 3.2 (0.9) | 3.1 (0.9) | 3.1 (0.7) | 0.41 | 1.8 (0.4) | 1.8 (0.4) | 1.8 (0.4) | 0.96 |
| Rµ,rest, WU | 1,374 (458) | 1,381 (406) | 1,483 (440) | 0.25 | 920 (301) | 1,070 (346) | 1,064 (363) | 0.12 |
| Rµ,hyp, WU | 412 (160) | 418 (131) | 462 (147) | 0.105 | 460 (126) | 538 (184) | 551 (168) | 0.04 |
| MRR | 3.9 (1.0) | 3.7 (0.9) | 3.5 (0.7) | 0.067 | 2.1 (0.3) | 2.1 (0.4) | 2.0 (0.4) | 0.71 |
| Data are presented as mean (SD). p-values in bold indicate statistical significance. CFR: coronary flow reserve; CMD: coronary microvascular dysfunction; MRR: microvascular resistance reserve; Qmax: hyperaemic absolute coronary flow; Qrest: resting absolute coronary flow; Rµ,hyp: hyperaemic absolute microvascular resistance; Rµ,rest: resting absolute microvascular resistance; SD: standard deviation; WU: Wood units | ||||||||