Table 1.
Correlation between P4HA3 expression and clinicopathological parameters.
| Characteristic | P4HA3low | P4HA3high | P value |
|---|---|---|---|
| N | 131 | 49 | |
| Gender, n (%) | 0.642 | ||
| Male | 80 (71.4 %) | 32 (28.6 %) | |
| Female | 50 (74.6 %) | 17 (25.4 %) | |
| Age (years), n (%) | 0.019 | ||
| ≤65 | 75 (80.6 %) | 18 (19.4 %) | |
| >65 | 56 (65.1 %) | 30 (34.9 %) | |
| T-stage, n (%) | 0.008 | ||
| T1 | 8 (100 %) | 0 (0 %) | |
| T2 | 27 (90 %) | 3 (10 %) | |
| T3 | 76 (71.7 %) | 30 (28.3 %) | |
| T4 | 20 (57.1 %) | 15 (42.9 %) | |
| N-stage, n (%) | < 0.001 | ||
| N0 | 76 (80.9 %) | 18 (19.1 %) | |
| N1 | 37 (78.7 %) | 10 (21.3 %) | |
| N2 | 18 (47.4 %) | 20 (52.6 %) | |
| M-stage, n (%) | 0.235 | ||
| M0 | 129 (74.1 %) | 45 (25.9 %) | |
| M1 | 2 (40 %) | 3 (60 %) | |
| Pathologic stage, n (%) | 0.018 | ||
| stageⅠ | 7 (100 %) | 0 (0 %) | |
| stage Ⅱ | 69 (80.2 %) | 17 (19.8 %) | |
| stage Ⅲ | 53 (65.4 %) | 28 (34.6 %) | |
| stage Ⅳ | 2 (40 %) | 3 (60 %) | |
| Tumor site, n (%) | 0.394 | ||
| Rectum | 65 (75.6 %) | 21 (24.4 %) | |
| Colon | 65 (69.9 %) | 28 (30.1 %) | |
| Histological type, n (%) | 0.221 | ||
| Adenocarcinoma | 123 (71.5 %) | 49 (28.5 %) | |
| Mucinous adenocarcinoma | 7 (100 %) | 0 (0 %) | |
| Degree of differentiation, n (%) | 0.040 | ||
| Moderately differentiated | 120 (76.9 %) | 36 (23.1 %) | |
| Poorly differentiated | 8 (50 %) | 8 (50 %) | |
| Vascular recidivism, n (%) | 0.356 | ||
| No | 116 (74.4 %) | 40 (25.6 %) | |
| Yes | 15 (65.2 %) | 8 (34.8 %) | |
| Lymphatic recidivism, n (%) | 0.013 | ||
| No | 101 (78.3 %) | 28 (21.7 %) | |
| Yes | 30 (60 %) | 20 (40 %) | |
| Neurorecidivism, n (%) | 0.134 | ||
| No | 121 (75.2 %) | 40 (24.8 %) | |
| Yes | 10 (55.6 %) | 8 (44.4 %) |