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. Author manuscript; available in PMC: 2024 Aug 14.
Published in final edited form as: Biomacromolecules. 2023 Jul 21;24(8):3638–3646. doi: 10.1021/acs.biomac.3c00385

Figure 4:

Figure 4:

Cytotoxicity evaluation of APCs in HER2+/− cells. (a) The cell viability of free antibody (both HER2 and IgG), comparative cytotoxicity of APC-Plow and APC-Phigh in MCF10A (HER2-) cells. (b) The cell viability of free antibody (both HER2 and IgG), comparative cytotoxicity of APC/Plow and APC/Phigh in SKOV3 (HER2+) cells. (c) Receptor expression quantification of HER2 in four different cell lines. (d) Specificity evaluation of APCs in SKBR3 cell using dye tagged secondary antibody. (e) Comparative cytotoxicity study of HER2/APC with Kadcyla® ADC in SKBR3 (HER2+) cell.