. 2024 Jun 3;24:125. doi: 10.1186/s12874-024-02254-x

Table 4.

Summary of the selected CpGs mediators with a %TE > 5 by the mHIMA2 models

Method^a	CpG	Chrom	Gene	$\hat{α}$	$\hat{β}$	%TE^b	P-value
mHIMA2-RA	cg20460771	1	PTAFR	0.0211	-0.0572	5.2398	0.0019
	cg06040872	17	CCL18	0.0157	-0.1092	7.4323	0.0002
	cg16893868	19	LILRA2	-0.0155	0.1015	6.8344	< 0.0001
mHIMA2-PSR	cg13917614	17	CNP	0.0230	-0.1936	19.3678	0.0001
	cg03164561	2	NMUR1	0.0149	-0.1146	7.4161	0.0015
	cg03605454	4	RP11-526A4.1	0.0154	-0.1033	6.9094	0.0028
	cg09529165	17	-	0.0198	-0.2038	17.5660	< 0.0001
	cg01500140	19	LIM2	0.0157	-0.1393	9.5028	0.0013
	cg16893868	19	LILRA2	-0.0155	0.1117	7.5217	0.0012
mHIMA2-IPW	cg13917614	17	CNP	0.0230	-0.0717	7.1289	0.0001
mHIMA2-IPW	cg16893868	19	LILRA2	-0.0157	0.0913	6.1962	0.0001
mHIMA2-OW	cg13917614	17	CNP	0.0230	-0.0737	7.3785	0.0001
mHIMA2-OW	cg16893868	19	LILRA2	-0.0155	0.0916	6.1681	0.0001

^aMethod denotes the combination of the mHIMA2 approach and different confounding adjustment methods. Such as mHIMA2-OW denotes the mHIMA2 method with overlapping weighting

^b%TE total effect proportion

- No related genes were found