Table 4. Odds ratio for lung cancer according to the number of cancer cases by category of first-degree relatives.
| Cancer in first-degree relatives1 | Cases (n = 334) | Controls (n = 578) | OR2 (95% CI) |
|---|---|---|---|
| None3 | 230 | 429 | 1.00 |
| Mother | |||
| Any | 27 | 43 | 1.10 (0.64 – 1.91) |
| Not tobacco-related | 10 | 19 | 0.88 (0.38 – 2.04) |
| Tobacco-related4 | 14 | 19 | 1.37 (0.64 – 2.94) |
| Lung | 3 | 5 | 1.01 (0.21 – 4.97) |
| Father | |||
| Any | 28 | 43 | 1.09 (0.63 – 1.89) |
| Not tobacco-related | 8 | 17 | 0.87 (0.34 – 2.19) |
| Tobacco-related4 | 16 | 19 | 1.48 (0.70 – 3.13) |
| Lung | 4 | 7 | 0.68 (0.18 – 2.53) |
| Siblings | |||
| Any | 52 | 61 | 1.20 (0.76 – 1.87) |
| Not tobacco-related | 14 | 21 | 1.10 (0.52 – 2.35) |
| Tobacco-related4 | 31 | 33 | 1.29 (0.73 – 2.30) |
| Lung | 7 | 7 | 1.05 (0.34 – 3.21) |
1
No cancer was reported in the offspring
2
Adjusted for gender, age, socioeconomic status (four levels), smoking (pack-years), and number of siblings (group of siblings)
3
Reference category
4
Bladder, larynx, esophagus, oral cavity, pharynx, pancreas, kidney and renal pelvis.