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. 2024 Apr;34(4):530–538. doi: 10.1101/gr.278810.123

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© 2024 Tierney et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

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Figure 3. — Ribosome paths through mRNA. (Top) An example of an RNA with three start codons (green for AUG and light green for CUG) located in two different reading frames depicted as differentially shaded horizontal bars. The translation of this mRNA is represented as a set of translons below; ribosome paths, further below; and ribosome decision graphs (RDGs), the bottom. RNA regions scanned by the ribosome are shown in dark gray; the vertical path in light gray represents the postterminating small ribosomal subunit that continues scanning and remains initiation-competent.