Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Apr;34(4):530–538. doi: 10.1101/gr.278810.123

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 Tierney et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Figure 5. — Representation of translation of human mRNAs. (A) The top plots are A-site subcodon footprint densities for NXT1 and NRAS mRNAs colored to match the best-supported reading frame below in the ORF plots, in which AUGs are in white and stops are in black. Further below are RDG representations with translons colored to match the translated frame. The CDS starts are treated deterministically, and unproductive RiboPaths are not shown. (B) Densities of ribosome A-site footprints obtained from ribosome profiling under different conditions (NRAS) or from different cells (NXT1). RDGs are shown below each density plot, with translons colored as a heatmap reflecting relative translation efficiencies. Branching points (starts) are also colored as heatmaps, reflecting the inferred probability of their initiation. The probabilities of translation initiation are shown as fraction decimals, whereas the relative translation efficiencies of each path are shown as percentages.