Table 2. Data on acute toxicity and tumour response.
| Patient/tumour | Contrast-enhancing tumour size at various time points (mm) | Acute toxicity | Tumour response | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 1 week follow-up | 1 month follow-up | 3 months follow-up | Systemic adverse events | Radiation dermatitis | Other grade ≥ 2 toxicity | Tumour response at 3 months | Tumour response at last follow-up | |
| 1 | 59 × 48 | 57 × 42 | 48 × 27 | 0 × 0 | None | Grade 1 | None | CR/Replacement Fibrosis | No PD at 34 months |
| 2 Left | 24 × 24 | 26 × 21 | 24 × 21 | 15 × 15 | None | Grade 1 | None | CR/Replacement Fibrosis | No PD at 33 months |
| 2 Right | 27 × 23 | 27 × 25 | 23 × 24 | 22 × 18 | None | Grade 1 | None | PR | No PD at 33 months |
| 3 | 23 × 15 | 19 × 22 | 17 × 14 | 0 × 0 | None | Grade 2 | None | CR/Replacement Fibrosis | No PD at 29 months |
| 4 | 53 × 42 | 43 × 39 | 34 × 28 | 11 × 16 | None | Grade 1 | None | PR | PD at 8 months |
| 5 | 38 × 28 | 17 × 20 | 16 × 14 | 14 × 14 | None | Grade 1 | None | CR/Replacement Fibrosis | No PD at 12 months |
| 6 | 37 × 27 | 36 × 32 | 35 × 27 | 30 × 26 | None | Grade 1 | None | SD | PD at 15 months |
| 7 | 62 × 45 | 35 × 31 | 23 × 24 | 0 × 0 | None | Grade 1 | None | CR/Replacement Fibrosis | No PD at 3.9 months |
| 8 | 88 × 68 | 102 × 63 | 61 × 63 | NA | None | Grade 1 | None | NA | No PD at 1 month |
| 9 | 25 × 12 | 29 × 8 | 22 × 7 | 28 × 16 | None | Grade 1 | None | PD | PD at 3 months |
| 10 | 38 × 31 | 38 × 31 | 29 × 27 | 29 × 27 | None | Grade 3 | None | CR/Replacement Fibrosis | No PD at 18 months |
| 11 | 24 × 5 | 10 × 3 | 0 × 0 | 0 × 0 | None | Grade 0 | None | CR/Replacement Fibrosis | No PD at 18 months |
| 12 | 35 × 21 | 31 × 18 | 35 × 11 | 26 × 10 | Possible Grade 1 Allergic Reaction | Grade 1 | None | PR | No PD at 14 months |
| 13 | 23× 29 | 28 × 21 | 19 × 18 | 18 × 12 | None | Grade 1 | None | PR | No PD at 12 months |
| 14 Left | 92 × 11 | 62 × 12 | 65 × 14 | 65 × 14 | None | Grade 3 | None | CR/Replacement Fibrosis | No PD at 9 months |
| 14 Right | 46 × 13 | 38 × 10 | 0 × 0 | 0 × 0 | None | Grade 1 | None | CR/Replacement Fibrosis | No PD at 9 months |
| 15 | 76 × 35 | 63 × 15 | 61 × 13 | 58 × 15 | None | Grade 1 | None | PR | No PD at 12 months. |
| 16 | 39 × 28 | 34 × 28 | 34 × 28 | 35 × 31 | None | Grade 1 | None | SD | No PD at 8 months |
| 17 | 29 × 19 | 21 × 19 | 16 × 18 | 15 × 16 | None | Grade 1 | None | PR | No PD at 8 months |
| 18 | 46 × 50 | 52 × 41 | NA | NA | None | Grade 1 | None | NA | No PD at 1 week |
Patients were assigned numbers from 1 to 18, and for those with bilateral tumours, the left and right sides were described.
CR, complete response; NA, not available; PD, progressive disease; PR, partial response; SD, stable disease.