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. 2024 Jun 3;19(6):e0304576. doi: 10.1371/journal.pone.0304576

Table 1. Characteristics of pregnant women with syphilis by treatment status.

BPG Treatment No Documented BPG Treatment Total
n = 1,231
Documented n = 642 median (IQR)
n = 589 median (IQR) or n (%) p-value
Variable median (IQR) or n (%)
or n (%)
Sociodemographic Variables
Age (years) (n = 1218) 27.0 (23.0,32.0) 27.0 (23.0,32.0) 27.0 (23.0,32.0) 0.75
Marital Status (n = 1156)       0.94 
Married/Living with Partner 506 (88.3)  514 (88.2)  1020 (88.2) 
Single 67 (11.7)  69 (11.8)  136 (11.8) 
Age Categories (yrs) (n = 1218)     0.77 
16–19  29 (4.9)  37 (5.9)  66 (5.4) 
20–24  161 (27.4)  156 (24.8)  317 (26.0) 
25–29  182 (30.9)  204 (32.4)  386 (31.7) 
30–34  118 (20.1)  121 (19.2)  239 (19.6) 
35+  98 (16.7)  112 (17.7)  210 (17.3) 
Positive HIV Status (n = 1204) 238 (41.1) 274 (43.8)   512 (42.5)  0.34
Obstetric and Prenatal Care History
Parity (n = 1201)       0.59
130 (22.3)  118 (19.1)  248 (20.6) 
1–2  292 (50.0)  326 (52.9)  618 (51.5) 
3–4  132 (22.6)  142 (23.0)  274 (22.8) 
5+  30 (5.1)  31 (5.0)  91 (5.1) 
Gestational Age at Entry to ANC (n = 1088)     0.57 
4–14 weeks 99 (18.5)  110 (19.9)  209 (19.2) 
15–28 weeks 395 (74.0)  395 (71.3)  790 (72.6) 
≥ 28 weeks 40 (7.5)  49 (8.8)  89 (8.2) 
ANC Calendar Year (n = 1228)       <0.001 
2018  443 (75.2)  331 (51.8)  774 (63.0) 
2019  146 (24.8)  308 (48.2)  454 (37.0) 
Facility Type (n = 1231)       <0.001 
Health Center 282 (47.9)  240 (37.4)  522 (42.4) 
General Hospital 307 (52.1)  402 (62.6)  709 (57.6) 
Number BPG Doses Received (n = 1231) <0.001
0 0 642 (100) 642 (52.6)
1 147 (25.5) 0 147 (12.1)
2 23 (4.0) 0 23 (1.9)
3 407 (70.5) 0 407 (33.4)
Syphilis Test at ANC Entry (n = 1228) 588 (99.8) 636 (99.5)  1224 (99.7)  0.63* 
Sex Partner Referral for Therapy (n = 1231) 85 (14.4) 15 (2.3) 100(8.1) <0.001 
Adverse Birth Outcomes
Low Birthweight (<2500 gm) 0.07
(n = 837) 40 (9.9) 61 (14.1) 101 (12.1)
Preterm delivery (<37 weeks) (n = 861) 121 (32.2) 171 (42.8) 292 (37.6) 0.002