Table 4.
Previous studies investigating contact delayed hypersensitivity in rosacea patients
| Study | Country | Patch test series | No. of rosacea patients | No. of controls | Percentage of rosacea patients with positive reaction to ≥1 allergen | Percentage of controls with positive reaction to ≥1 allergen |
|---|---|---|---|---|---|---|
| Corazza et al. [8] (1997) | Italy | GIRDA standard series | 29 | _ | 41% | _ |
| Jappe et al. [9] (2005) | Germany, Austria, Switzerland | ICDRG standard series extended by DKG | 361 | _ | 38.2% | _ |
| Cakmak et al. [10] (2007) | Turkey | European Cosmetic Series | 25 | 20 | 32% | 0% |
| Jappe et al. [11] (2008) | Germany | ICDRG standard series extended by DKG | 78 | _ | 62.8% | _ |
| Pónyai et al. [12] (2012) | Hungary | Brial GmbH D-Greven series | 82 | _ | 35.4% | _ |
| Darlenski et al. [13] (2013) | Bulgaria | European Baseline Series | 28 | 32 | Equal | Equal |
| Diczig et al. [14] (2018) | Hungary | Unknown | 143 | _ | 37.8% | _ |
| Erdogan et al. [15] (2018) | Turkey | European Baseline Series | 65 | 60 | 32.3% | 20% |
| Cifci et al. [16] (2019) | Turkey | Nickel units from European Standard Series | 40 | 40 | 52.5% | 22.5% |
| Ozbagcivan et al. [17] (2020) | Turkey | European Cosmetic Series | 103 | 104 | 60.2% | 24% |
| Chen et al. [18] (2021) | China | Skin patch tests with C-1000 cosmetic series (Chemotechnique Diagnostics, Malmo, Sweden | 267 | 100 | 57.3% | 27% |
| Magdaleno-Tapial et al. [19] (2022) | Spain | Standard series of Spanish Contact Dermatitis and Skin Allergy Research Group | 200 | – | 46.5% | – |