Fig. 2.

High LRG-1 levels are associated with a poor prognosis and is an independent prognostic marker. Kaplan–Meier analysis comparing a cumulative breast cancer-specific survival and b cumulative overall survival of LRG-1 high (n = 133) versus LRG-1 low (n = 368) breast cancer patients. HR and 95% CI according to Mantel Haenszel and p-value according to log-rank (Mantel–Cox) are indicated. c The univariate and multivariate analysis is shown for patients with high LRG-1 versus patients with low LRG-1 serum levels. HR, 95%CI and p-values are shown. The cut-off (33.64 µg/ml) is determined as described in the methods section