TABLE 1.
Virus isolation and serology
| Group | Virus isolation (4 days p.i.)a
|
Serologyb (14 days p.i.) | MDT (days) | ||
|---|---|---|---|---|---|
| Lung (n = 3) | Trachea (n = 3) | Kidney (n = 3) | |||
| Sham infected | 0 | 0 | 0 | Negative | NDc |
| Italy/97 | 3 | 2 | 0 | 36 | ND |
| Scot/59 | 1 | 1 | 1 | 6 | ND |
| Eng/91 | 2 | 3 | 0 | 216 | 9d |
| Q20/95 | 2 | 3 | 0 | 36 | ND |
| HK156 | 3 | 3 | 1 | —e | 6.33 |
| HK220 | 3 | 3 | 1 | —e | 6.33 |
| HK728 | 3 | 3 | 0 | —f | 9.00 |
a
Number of mice in which virus was isolated.
b
Values represent CI-ELISA titer.
c
ND, no deaths occurred.
d
One mouse died on day 9 p.i. in experiment 2.
e
All HK infected mice were dead by day 14 p.i. when serum samples were taken for CI-ELISA.
f
Mouse serum not analyzed at 14 days p.i. since only two mice were alive.