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. 2024 Jun 3;15:4567. doi: 10.1038/s41467-024-48763-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Illustration of the collection of blood samples from a regional Swedish inception cohort comprising treatment-naïve pediatric patients referred for suspected pediatric IBD. The study findings were validated using the Norwegian population-based IBSEN III pediatric inception cohort and further confirmed in an independent third pediatric cohort. The graphics in this figure were created using Biorender.com. Abbreviations: IBD, inflammatory bowel disease.