Table 3.

Missense and silent mutations in samples categorized by the presence of driver mutations in EGFR and KRAS genes.

Sample type	Number of samples	Number of missense mutations	Number of silent mutations	Density missense (per sample, per site)	Density silent (per sample, per site)	dN/dS
Driver mutations in EGFR	69	14,700	6035	2.88E-06	3.86E-06	0.75 ± 0.03
No driver mutations in EGFR	2362	855,254	291,208	4.89E-06	5.44E-06	0.89 ± 0.01
Driver mutations in KRAS	160	80,537	24,213	6.80E-06	6.68E-06	1.02 ± 0.02
No driver mutations in KRAS	2271	789,200	272,442	4.69E-06	5.30E-06	0.89 ± 0.01